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ABOUT

Our Mission

NCSL approaches understanding brain function in health and disease with a dynamical systems and control perspective. Specifically, we use mathematical representations to characterize how environmental stimuli (images, sounds, etc.) or exogenous stimuli (e.g. drugs, stimulation treatment) impact neural activity and behavior, carefully accounting for latent variables that exist but that are difficult to measure experimentally. These techniques allow neuroscientists to explain variable and complex behaviors that arise in the presence of fixed options, and most importantly to then identify neural correlates that capture both stimuli and latent variables. Today, our lab focuses on developing computational, data-driven, and biological approaches to advance the knowledge of cortical dynamics driving new diagnostics and treatments for epilepsy and chronic pain.

RESEARCH

Our Work

Our lab focuses on developing computational, data-driven, and biological approaches to advance the knowledge of cortical dynamics driving new diagnostics and treatments for epilepsy and chronic pain.

Epilepsy

Epilepsy

Current Research
Chronic Pain

Chronic Pain

Current Research
Sensorimotor Control

Sensorimotor Control

Current Research
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PUBLICATIONS

Latest Publications

[J1] Kamali G, June-Smith R, Hays M, Coogan C, Crone NE, Kang JY, Sarma SV. Transfer Function Models for the Localization of Seizure Onset Zone from Cortico-Cortical Evoked Potentials. Frontiers Neurology. (accepted for publication)

[J2] Yang F, Duan W, Huang Q, et al. Modulation of Spinal Nociceptive Transmission by Sub-Sensory Threshold Spinal Cord Stimulation in Rats After Nerve Injury. Neuromodulation. 2020;23(1):36- 45. doi:10.1111/ner.12975

[J3] Gunnarsdottir KM, Gamaldo C, Salas RM, et al. A novel sleep stage scoring system: Combining expert-based features with the generalized linear model.J Sleep Res. 2020;29(5):e12991. doi:10.1111/jsr.12991

[J4] Saxena S, Sarma SV, Dahleh M. Performance Limitations in Sensorimotor Control: Trade-Offs Between Neural Computation and Accuracy in Tracking Fast Movements.Neural Comput. 2020;32(5):865-886. doi:10.1162/neco_a_01272

[J5] Breault MS, Fitzgerald ZB, Sacre P, Gale JT, Sarma SV, and Gonzalez-Martınez J. Non-motor brain regions in non-dominant hemisphere are influential in decoding movement speed. Frontiers in Neuroscience, 13:715, July 2019

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Events

15
Jun

Lab Meeting (NCSL) Presentation by Autumn Octavia Williams, PhD Student

Seminar Series
12:00 pm / 1:30 pm
29
Jun

Lab Meeting (NCSL)

Seminar Series
4:00 pm / 5:30 pm
13
Jul

Lab Meeting (NCSL)

Seminar Series
4:00 pm / 5:30 pm
View Calendar

LATEST NEWS

Our News And Insights

Our results solution combines implementation support, capability building and state-of-the-art diagnostic and analytic tools sally change.

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